Trigeminal Neuralgia
April 2018 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Trigeminal Neuralgia abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Trigeminal Neuralgia. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Trigeminal Neuralgia. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Trigeminal Neuralgia every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Acupuncture for the treatment of trigeminal neuralgia: A protocol for the systematic review of randomized controlled trials.
Authors:Kim JI, Kim HJ, Lee JJ, Jun JH, Choi TY, Lee MS
Institution:Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, Seoul. Seoul. Republic of Korea. Republic of Korea. Republic of Korea.
Journal:Medicine (Baltimore). 2018 Mar;97(11):e0108. doi: 10.1097/MD.0000000000010108.

2:Single-dose botulinum toxin type a compared with repeated-dose for treatment of trigeminal neuralgia: a pilot study.
Authors:Zhang H, Lian Y, Xie N, Chen C, Zheng Y
Institution:Department of Neurology, First Affiliated Hospital of Zhengzhou University, 1 Jianshe East R, Zhengzhou City, HeNan Province, 450052, People's Republic of China.
Journal:J Headache Pain. 2017 Aug 10;18(1):81. doi: 10.1186/s10194-017-0793-3.

3:Meta-Analysis on Safety and Efficacy of Microsurgical and Radiosurgical Treatment of Trigeminal Neuralgia.
Authors:Gubian A, Rosahl SK
Institution:Department of Neurosurgery, HELIOS Klinikum Erfurt, Erfurt, Germany. Electronic address:
Journal:World Neurosurg. 2017 Jul;103:757-767. doi: 10.1016/j.wneu.2017.04.085. Epub 2017 Apr 20.

4:Trigeminal Neuralgia: Toward a Multimodal Approach.
Authors:Spina A, Mortini P, Alemanno F, Houdayer E, Iannaccone S
Institution:Department of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Vita-Salute University, Milan, Italy. Electronic address:; Department of Clinical Neuroscience, Specialistic Neurorehabilitation of Neurological, Cognitive and Motor Disorders, San Raffaele Scientific Institute, Milan, Italy.
Journal:World Neurosurg. 2017 Jul;103:220-230. doi: 10.1016/j.wneu.2017.03.126. Epub 2017 Apr 2.

5:After microvascular decompression to treat trigeminal neuralgia, both immediate pain relief and recurrence rates are higher in patients with arterial compression than with venous compression.
Authors:Shi L, Gu X, Sun G, Guo J, Lin X, Zhang S, Qian C
Institution:Department of Neurosurgery and Anesthesiology, The First People's Hospital of Kunshan affiliated with Jiangsu University, Suzhou, P. R. China. Jiangsu, China. University, Yancheng, P. R. China. University, Yancheng, P. R. China. Kunshan affiliated with Jiangsu University, Suzhou, P. R. China. Kunshan affiliated with Jiangsu University, Suzhou, P. R. China. University, Nanjing, P. R. China.
Journal:Oncotarget. 2017 Jul 4;8(27):44819-44823. doi: 10.18632/oncotarget.14765.

6:A retrospective study of neurocombing for the treatment of trigeminal neuralgia without neurovascular compression.
Authors:Liang X, Dong X, Zhao S, Ying X, Du Y, Yu W
Institution:The Department of Neurosurgery, Hangzhou First People's Hospital, 261 Huan Sha Road, Shang Cheng District, Hangzhou, 310006, China.; Zhejiang Chinese Medical University, 548 Bin Wen Road, Bin Jiang District, Hangzhou, 310053, China.; The Department of Neurosurgery, Zhejiang Provincial Hospital of Traditional Chinese Medicine, 54 You Dian Road, Shang Cheng District, Hangzhou, 310006, China.
Journal:Ir J Med Sci. 2017 Nov;186(4):1033-1039. doi: 10.1007/s11845-016-1547-y. Epub 2017 Jan 6.

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