Ductal Carcinoma in Situ of the Breast
March 2021 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Ductal Carcinoma in Situ of the Breast. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Ductal Carcinoma in Situ of the Breast. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Ductal Carcinoma in Situ of the Breast every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Comparison of breast ductal carcinoma in situ and ductal carcinoma in situ with microinvasion, and analysis of axillary lymph node metastasis.
Authors:Zhang G, Li C, Tian G, Cheng X, Li Y, Ma L
Institution:Breast Center.
Journal:Medicine (Baltimore). 2020 Dec 24;99(52):e23593. doi: 10.1097/MD.0000000000023593.

2:Comparison of local recurrence after mastectomy for pure ductal carcinoma in situ with close or positive margins: A meta-analysis.
Authors:Kim D, Ki Y, Kim W, Park D, Joo J, Jeon H, Nam J
Institution:Department of Radiation Oncology, Biomedical Research Institute, Pusan National University Hospital and Pusan National University School of Medicine, Busan, Korea.
Journal:J Cancer Res Ther. 2020 Oct-Dec;16(6):1197-1202. doi: 10.4103/jcrt.JCRT_160_19.

3:Do surgical margins matter after mastectomy? A systematic review.
Authors:Bundred J, Michael S, Bowers S, Barnes N, Jauhari Y, Plant D, Maishman T, Cutress R, Holleczek B, Dodwell D, Bundred N
Institution:College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. Manchester University NHS Foundation Trust, Wythenshawe, Manchester, M23 9LT, UK; University of Manchester, Manchester, M13 9PT, UK. Electronic address: Bundredn@manchester.ac.uk.
Journal:Eur J Surg Oncol. 2020 Dec;46(12):2185-2194. doi: 10.1016/j.ejso.2020.08.015. Epub 2020 Aug 28.

4:Sentinel lymph node biopsy may be unnecessary for ductal carcinoma in situ of the breast that is small and diagnosed by preoperative biopsy.
Authors:Uemoto Y, Kondo N, Wanifuchi-Endo Y, Asano T, Hisada T, Nishikawa S, Katagiri Y, Terada M, Kato A, Okuda K, Sugiura H, Kato H, Takahashi S, Toyama T
Institution:Departments of Breast Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya.
Journal:Jpn J Clin Oncol. 2020 Dec 16;50(12):1364-1369. doi: 10.1093/jjco/hyaa151.

5:Preoperative breast MRI in management of patients with needle biopsy-proven ductal carcinoma in situ (DCIS).
Authors:van Bekkum S, Ter Braak BPM, Plaisier PW, van Rosmalen J, Menke-Pluijmers MBE, Westenend PJ
Institution:Department of Surgery, Albert Schweitzer Hospital, Dordrecht, the Netherlands. Department of Pathology, Laboratory of Pathology, Dordrecht, the Netherlands; Regional screening organization South West the Netherlands, Maasstadweg 12, 3079 DZ, Rotterdam, The Netherlands. Electronic address: pwestenend@paldordrecht.nl.
Journal:Eur J Surg Oncol. 2020 Oct;46(10 Pt A):1854-1860. doi: 10.1016/j.ejso.2020.05.028. Epub 2020 Jun 24.

6:Ductal carcinoma in situ on digital mammography versus digital breast tomosynthesis: rates and predictors of pathologic upgrade.
Authors:Kim G, Mikhael PG, Oseni TO, Bahl M
Institution:Department of Radiology, Division of Breast Imaging, Massachusetts General Hospital, 55 Fruit Street, WAC 240, Boston, MA, 02114, USA. mbahl1@mgh.harvard.edu.
Journal:Eur Radiol. 2020 Nov;30(11):6089-6098. doi: 10.1007/s00330-020-07021-2. Epub 2020 Jun 26.

7:Noncalcified Ductal Carcinoma In Situ (DCIS): Rate and Predictors of Upgrade to Invasive Carcinoma.
Authors:Lamb LR, Kim G, Oseni TO, Bahl M
Institution:Massachusetts General Hospital/Department of Radiology, 55 Fruit Street, WAC 240, Boston, MA 02114. Electronic address: mbahl1@mgh.harvard.edu.
Journal:Acad Radiol. 2021 Mar;28(3):e71-e76. doi: 10.1016/j.acra.2020.02.011. Epub 2020 Mar 26.

8:ASO Author Reflections: Is Sentinel Lymph Node Biopsy Necessary in Patients with Ductal Carcinoma In Situ with Microinvasion Diagnosed on Core Biopsy?
Authors:Phantana-Angkool A, White RL Jr
Institution:Division of Surgical Oncology, Department of Surgery, Levine Cancer Institute, Carolinas Medical Center, Charlotte, NC, USA. Richard.White@carolinashealthcare.org.
Journal:Ann Surg Oncol. 2020 Dec;27(Suppl 3):733-734. doi: 10.1245/s10434-019-08006-2. Epub 2020 Jan 8.

9:Ductal Carcinoma In Situ (DCIS) at Breast MRI: Predictors of Upgrade to Invasive Carcinoma.
Authors:Lamb LR, Lehman CD, Oseni TO, Bahl M
Institution:Massachusetts General Hospital, Department of Radiology, 55 Fruit Street, WAC 240, Boston, MA 02114. Electronic address: mbahl1@mgh.harvard.edu.
Journal:Acad Radiol. 2020 Oct;27(10):1394-1399. doi: 10.1016/j.acra.2019.09.025. Epub 2019 Nov 4.

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